Recruitment of neurons into neural ensembles based on dendritic plateau potentials

TitleRecruitment of neurons into neural ensembles based on dendritic plateau potentials
Publication TypeConference Paper
Year of Publication2018
AuthorsGao, P. P., Graham J. W., Angulo S. L., Dura-Bernal S., Hines M. L., Lytton WW., & Antic S. D.
Conference NameSociety for Neuroscience 2018 (SFN '18)
KeywordsSFN, Society for Neuroscience
Abstract

Experimental observations have shown that glutamatergic inputs to the basal dendrites of cortical pyramidal neurons activate AMPA and NMDA receptors, which can bring the dendrites into a long-lasting depolarized state: a dendritic plateau potential. These sustained depolarizations push the cell body towards spike threshold and reduce the membrane time constant. In such a ``